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Immunomedics is a New Jersey-based
biopharmaceutical company focused on the development
of monoclonal, antibody-based products for the targeted
treatment of cancer, autoimmune and other serious
diseases. We have developed a number of advanced proprietary
technologies that allow us to create humanized antibodies
that can be used either alone in unlabeled or “naked”
form, or conjugated with radioactive isotopes, chemotherapeutics
or toxins, in each case to create highly targeted
agents. Using these technologies, we have built a
pipeline of therapeutic product candidates that utilize
several different mechanisms of action. We have recently
licensed our lead product candidate, epratuzumab,
to UCB, S.A. for the treatment of all autoimmune disease
indications worldwide. We have retained the rights
for epratuzumab in oncology indications for which
UCB has been granted a buy-in option. UCB has development,
manufacture and commercialization rights, and is responsible
for all clinical trials evaluating epratuzumab for
the treatment of patients with moderate and severe
lupus. At present, there is no cure for lupus and
no new lupus drug has been approved in the U.S. in
the last 40 years. We believe that our portfolio of
intellectual property, which includes approximately
108 patents issued in the United States, and more
than 250 other issued patents worldwide, protects
our product candidates and technologies. We also have
a majority ownership in IBC Pharmaceuticals, Inc.,
which is developing a novel dock and lock methodology,
and a new method of delivering imaging and therapeutic
agents selectively to disease, especially different
solid cancers (colorectal, lung, pancreas, etc.),
by proprietary, antibody-based, pretargeting methods.
We have transitioned our focus away
from the development of diagnostic imaging products
in order to accelerate the development of our therapeutic
product candidates. Consistent with our de-emphasis
on our diagnostic business, we no longer commercialize
CEA-Scan®. LeukoScan® will continue to be
manufactured and commercialized by us in territories
where regulatory approvals have been granted. Furthermore,
as of June 30, 2006, research and development into
diagnostic product candidates was no longer a material
portion of our business.

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